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Fluoxetine falls into the category of anti-depressants known as SSRIs(Selective Serotonin Reuptake Inhibitors). Doctors prescribe it for treating depression. Moreover, it is prescribed to overcome the symptoms of OCD or obsessive-compulsive disorder and a few other psychiatric illnesses e.g., Bulimia Nervosa. Interestingly, it has also been employed to treat severe symptoms of premenstrual syndrome (PMS).

Pharmacological Action

Prozac is a drug that works by increasing the levels of a substance called serotonin in the blood that helps with uplifting mood. It takes 4-6 weeks to exert its action. Prozac pill has to be used for a long time for significant improvement and tapering it off slowly under the supervision of your medical practitioner is highly recommended.

Mode of Indication, Dosage, and Duration of Treatment

Instructions about use should be read carefully before taking fluoxetine. Usually, it is recommended to take fluoxetine 20 mg once a day; preferably after having a healthy breakfast. However, if your doctor advises you to take it twice daily then you should take it at breakfast and then at noon. It has to be taken orally and the dose should not exceed 80 mg per day. For people who can not take it orally, liquid preparations are also available. The risk of overdose is more with liquid preparations so they should be measured carefully using a scoop. Fluoxetine takes 4-5 weeks to work so you should patiently for the results.

Precautions

Following precautionary measures should be taken before or when using Fluoxetine:

  • Get tested for drug allergies as Fluoxetine has some inactive ingredients which can cause an allergic reaction.

  • Share your complete personal and family history with your doctor. Specifically mention the history of psychiatric illnesses, eating disorders, substance abuse, liver disease, electrolyte imbalance, etc.

  • Let your doctor know about all the medicines, multivitamins, and any herbal preparations that you are using.

  • Let your doctor know about any heart condition you suffer from or run in your family.

  • Avoid the use of alcoholic beverages or drugs when taking Fluoxetine.

  • Avoid driving or doing work that requires extreme mental focus because using Prozac can make you drowsy.

  • The liquid preparation contains alcohol. In case of a positive history of liver disease, diabetes, or alcohol dependence do not use Fluoxetine available in liquid form.

  • Using Fluoxetine may cause problems with your vision. Get your eyesight checked before starting to use fluoxetine and if you experience any abnormal symptoms like nausea, pain in the eyes, changes in vision, etc. talk to your doctor immediately.

Side Effects

Using Prozac can cause many side effects. Keep a close eye on your symptoms and if you notice anything abnormal consult your doctor.

Given below are some common side effects of Prozac:

  • Anxiety

  • Difficulty falling asleep or staying awake

  • Nausea

  • Dry Mouth

  • Diarrhea

  • Heartburn

  • Fatigue

  • Drowsiness

  • Loss of appetite

  • Uncontrollable shaking of limbs

  • Weight loss

  • Decreased Libido

Some alarming side effects which should be catered to immediately are :

  • Rash or hoves

  • Fever

  • Itching

  • Joint Pain

  • Shortness of Breath

  • Irregular heartbeat

  • Swelling of different body parts

  • Seizures

  • Bleeding or bruising

Missed Dose

It is recommended to take the missed dose when you remember it. However, never take it if the time for the next one has approached. Taking doses at short interval is not recommended. Continue with your normal schedule if you won t be able to make up for a missed dose.

Overdose

If a person overdoses they will be confused, agitated, may have involuntary body movements, irregular heart beat, and other symptoms. They may get dizzy or start hallucinating. Whatever the situation may be immediately transfer them to the hospital or call emergency services.

Interaction with Other Drugs

Fluoxetine can give you serious allergic or drug reactions when taken along with some other medications.

Some of these are :

  • Ibuprofen

  • Wrafrain

  • Clopidogrel

  • MAO Inhibitors (Linezolid,Methylene Blue,Phenelzine)

  • Aspirin

  • Anti histamines

  • Vinblastine

  • Anti arrythmics

  • Diazepam

  • Muscle Relaxants

  • Opiods

These are just some drugs. Fluoxetine stays in your system for days and predicting its interaction with other drugs is not an easy task. So, mention all the medications you are taking to your doctor very responsibly to avoid any harmful drug interactions.