Usage

Aldactone is a potent drug to prevent excess absorption of salt. It acts as a stabilizer for blood potassium so it doesn't exceed the average level. 

The drug resolves the following issues:

  • Hypertension
  • Edema
  • Hypokalemia
  • Heart failure
  • Hyperaldosteronism

Dosage & Administration

Aldactone is prescribed by a physician and should be consumed accordingly. It's administered orally before evening to prevent stomach upset or frequent urination. However, if you experience stomach upset, consume the drug with a glass of milk or a fatty meal.

Aldactone comes in a liquid form. Ensure you shake the contents of the bottle properly before consumption. To get an accurate measurement, use a medical dosing device instead of an eating spoon. Also, if you prefer to take medicine without food, ensure you continue that way until the treatment is over. 

If you're consuming Aldactone tablets, swallow them with water but not on an empty stomach. The physician will prescribe Aldactone based on your weight (for pediatric patients), health condition, and treatment response. 

Don’t ingest more than the recommended dose or discontinue treatment without consulting a physician. Abrupt discontinuation of Spironolactone will worsen your health condition. 

  • Dosage for water retension: Adults should consume between twenty-five to two hundred milligrams daily for at least five days.
  • Dosage for hypertension: Adults should consume between fifty to hundred milligrams daily for at least two weeks.
  • Dosage for congestive heart failure: Consume 25 milligrams daily if the potassium level is ≦ 5 milliequivalents per liter and the creatinine is ≦ 2.5 milligrams per deciliter.
  • Dosage for low blood potassium: Consume between 25 - 100 milligrams daily.
  • Dosage for hyperaldosteronism: 400 milligrams for four days

Precautions

The following precautionary measures should be adhered to:

  • Inform your physician if you’ve experienced:
    • Allergies
    • Chronic kidney disease
    • Liver problems
    • Electrolyte disorder
    • Heart disease
  • Avoid consuming Aldactone if you’ve experienced:
    • Hyperkalemia
    • Urinary retention
    • Hypocortisolism
  • Avoid combining Spironolactone with another water pill such as eplerenone.
  • Avoid consuming low-sodium salt or potassium supplements. A diet that contains plenty salt will increase water retention and reduce the efficacy of Aldactone.
  • Limit the intake of foods that contain potassium such as potatoes, bananas, beans, and avocados.
  • Avoid consuming alcohol while on Aldactone therapy.
  • Avoid activities that require you to be alert, such as driving machines.
  • Don’t get out of bed too fast to prevent dizziness.
  • Geriatric patients may suffer severe side effects. Therefore, care should be taken when recommending Aldactone to them.
  • Pregnant women should only consume Aldactone if its benefits outweigh its risks.
  • Spironolactone might pass into breast milk. Therefore, patients should consider an alternative feeding method.
  • Aldactone might affect some lab test results. Therefore, your physician about the drugs you’re consuming.
  • If you’re treating hypertension using Aldactone, check the readings regularly. High BP doesn’t have symptoms. As a result, you won’t be able to know when you’re unwell.
  • If your health condition doesn’t improve, ensure you inform a doctor.

Side Effects

You may experience these side effects when consuming Aldactone, but call a physician if they last longer than necessary:

  • Stomach upset
  • Dizziness
  • Lightheadedness
  • Nausea
  • Headache

Aldactone may cause serious effects such as:

  • Recurrent bouts of vomiting
  • Polydipsia
  • Fever
  • Sore throat
  • Sexual dysfunction
  • Gynecomastia
  • Jaundice
  • Dark urine
  • Amenorrhea
  • Bleeding after menopause

Missed Doses

Don’t consume any dose that you’ve missed unless the time for the next one isn’t near. Avoid taking double doses to make up for a missed dose.

Overdose

Contact your local poison control team if you or someone has consumed an overdose of Aldactone. Common symptoms to look out for are difficulty in breathing and unconsciousness.

Drug Interactions

Spironolactone may interact with these drugs:

  • Aspirin
  • Metoprolol
  • Atorvastatin
  • Lisinopril
  • Protonix
  • Furosemide
  • Gabapentin
  • Vitamin D3
  • Levothyroxine
  • Carvedilol
  • Lasix
  • Metformin
  • Coreg
  • Levothyroxine
  • Omeprazole
  • Clopidogrel
  • Potassium chloride
  • Prednisone
  • Alprazolam

Certain food ingredients may increase your blood pressure or make the edema worse. Ensure you inform your doctor and the laboratory personnel about the drugs you’re consuming. If you’re consuming opioids, cough medicines, or weight loss pills, ask a consultant to prescribe a safe way of combining it with Aldactone.

Patient Information

  • Avoid sharing this medication with another patient.
  • Monitor your potassium levels, liver function, kidney function, and blood pressure regularly.
  • If you’re treating hypertension, positive lifestyle changes can increase the efficacy of Aldactone. These include exercise, reducing stress, and consuming a DASH diet, which consists of fruits, vegetables, fish, low-fat dairy, poultry, whole grains, and legumes. 
  • Store Aldactone away from direct sunlight. Also, don’t store it on the bathroom shelf to prevent moisture accumulation.
  • Avoid flushing Aldactone in the toilet or kitchen sink. Contact a physician or your local waste disposal company to know the best and safe options available.